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Ever since Allergan (AGN) struck an unusual deal last month to sell patents for the Restasis eye treatment to a Native American tribe, the drug maker has been accused of using a clever legal tactic to forestall low-cost generic competition to a big-selling product.

Now, one organization is attempting to quantify the potential cost to the U.S. health care system, and the number is a whopper — Americans would pay an extra $10.7 billion if a generic version of Restasis is unavailable between 2018 and 2024, when the existing patents on the medicine are due to expire.

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“It’s a big number, isn’t it?” said Dan Kistner, senior vice president of pharmacy solutions, at Vizient, a group-purchasing organization for more than 3,000 hospitals around the U.S., which rummaged through various data sources to work up this estimate.

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